ArthramidVet® is used by veterinarians everyday around the world for the treatment of joint lameness in horses. Multiple published studies from high profile institutions, and treating thousands of equine patients across all equestrian disciplines, show that ArthramidVet® is a safe and effective treatment for osteoarthritis and joint lameness in animals. Explore this page for more information and to access findings from studies of ArthramidVet® 2.5% iPAAG.
ArthramidVet® White Paper
Veterinarians: Get your copy of our 24 page white paper today, covering Treatment of Joint Lameness, Pathophysiology, Manufacturing, Mechanism of Action, Clinical Safety and Putting it into Practice.
Scientific Publications
Lowe J, de Clifford L, Julian A, Koene M. Histologic and cytologic changes in normal equine joints after injection with 2.5% injectable polyacrylamide hydrogel reveal low-level macrophage-driven foreign body response. JAVMA 2024
de Clifford, L.D., Lowe, J.N., McKellar, C.D., Bolwell, C., and David, F. (2021). A double-blinded positive control study comparing the relative efficacy of 2.5% polyacrylamide hydrogel (PAAG) against triamcinolone acetonide (TA) and sodium hyaluronate (HA) in the management of middle carpal joint lameness in racing Thoroughbreds.
de Clifford, L.D., Lowe, J.N., McKellar, C.D., Bolwell, C., and David, F. (2019). Use of a 2.5% Cross-Linked Polyacrylamide Hydrogel in the Management of Joint Lameness in a Population of Flat Racing Thoroughbreds: A Pilot Study
Henrikson, M., Overgaard, A., and Bliddal, H. (2017). Initial Estimates of Efficacy of Intra-Articular 2.5% Polyacrylamide Hydrogel for the Treatment of Knee Osteoarthritis: An Observational Proof-of-Concept Study
Bathe, A.P., Read, R.M., and Briggs, C. (2016). Intra-articular polyacrylamide hydrogel for the treatment of 20 horses with non-responsive osteoarthritis of the interphalangeal joints: a prospective study
Christensen, L., Illigen, K.E., Hansen, M., Sarvaa, R., and Conogham, P.G. (2016). Synovial incorporation of polyacrylamide hydrogel after injection into normal and osteoarthritic animal joints
Tnibar et al (2015). An international multi-centre prospective study on the efficacy of an intraarticular polyacrylamide hydrogel in horses with osteoarthritis: a 24 months follow-up
Tnibar et al (2014). Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study
Janssen, I., Koene, M., and Lischer, C. (2012). Intraarticular application of polyacrylamide hydrogel as a treatment of osteoarthritis in the distal interphalangeal joint: Case series with 12 horses
Testimonials
Dr Stuart Vallance
ADVANTAGE EQUINE VETERINARY PRACTICE
ASCOT VALE, VIC, AUSTRALIA
I have utilised hundreds of doses of 2.5% PAAG gel since 2014, and during this period I have learnt how to maximise its benefit”
Dr Stuart Vallance
ADVANTAGE EQUINE VETERINARY PRACTICE
ASCOT VALE, VIC, AUSTRALIA
I have utilised hundreds of doses of 2.5% PAAG gel since 2014, and during this period I have learnt how to maximise its benefit in my caseload of predominantly Thoroughbred racehorses. In my opinion, it can minimise the use of intra-articular corticosteroids or other joint therapies used in Thoroughbred stables. 2.5% PAAG is not a cortisone and shouldn’t be expected to diminish acute inflammation like corticosteroids do. In my opinion, it appears to have the greatest clinical effect in appropriately diagnosed joints with low-grade performance limiting lameness that are treated early in the horse’s preparation, or if utilised within a preparation given time (approximately 3 weeks) before one would expect to see a marked clinical improvement.
I have utilised hundreds of doses of 2.5% PAAG gel since 2014, and during this period I have learnt how to maximise its benefit”
Dr Marc Koene
TIERKLINIK LÜSCHE GMBH EQUINE HOSPITAL
NORTHERN GERMANY
I was one of the first vets to use Arthramid worldwide and the results are quite astonishing”
Dr Marc Koene
TIERKLINIK LÜSCHE GMBH EQUINE HOSPITAL
NORTHERN GERMANY
I was one of the first vets to use Arthramid worldwide and have now used Arthramid for over 10 years in our clinic. We have injected over a thousand horses and have found it to be very safe. It has been a major game-changer in the way we treat OA in our patients. We have fantastic results with really frustrating cases and are still working on new indications and treatment schemes for the product. We are also looking into the ongoing research, especially around the Mode of Action.
There are not many “new” products implemented in our OA Toolbox in recent years. Regenerative medicine and Bisphosphonates were the greatest new assets and I rate Arthramid Vet in the same league. 2.5% PAAG gives us the chance to minimize corticosteroids and we have no threats of “doping positive “ cases. As well, some horses, instead of being destroyed, are happily back in business. I would encourage every orthopaedic vet to try the product. They will love it, if their case selection is appropriate.
I was one of the first vets to use Arthramid worldwide and the results are quite astonishing”
